Review: Niod – Copper Amino Isolate Serum (CAIS 3 1:1)

Where to purchase: Available from the Deciem Store: LINK / Cult Beauty: LINK / Adore Beauty: LINK / Look Fantastic: LINK / Beauty Bay: LINK / Feel Unique: LINK

Price: £65

Volume: 30ml

Made in: Canada

What is it?: A well-ageing serum meant to stimulate collagen in the skin and help with wound healing. Compared to CAIS2, this now contains Fully Stable Copper Peptide so you don’t need to mix this with another bottle before using!

What does it do?: It’s pro-collagen and maintaining the look of ”good” skin. Stimulating collagen is supposed to help keep the skin looking supple and reduce the look of lines + wrinkles (with the help of additional added peptides).

Supposedly Good for: All Skin Types

What I think: Dry Skins may prefer the Balm Version LINK. I also think this might not be suitable for sensitive skins, especially for those with broken skin + wounds (may sting).


Vegan?: Yes

Cruelty Free?: Yes

How long does it last after opening?: 6 Months

pH: 5.7-6.7

Packaging: Glass bottle with a dropper.

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Directions: ”Apply to face AM and PM. Apply as the first step after cleaning before the application of thicker serums or creams.” (From the Niod Website). Can’t be used with Acids or Vitamin C (read the instructions for more directions).

How I use it: I use this in the PM (I don’t use this at the same time as exfoliating acids). I do have to slide this along the skin and dispense because this is so expensive and so lightweight and watery, I don’t want to waste any of this product getting absorbed onto my fingers instead.

Key Ingredients: 1.0% Copper Tripeptide-1 (GHK-Cu) + 1.0% Tripeptide-1 (GHK): Supposedly the levels of these drop in the skin during the ageing process; so these are added back onto the skin using this serum. These help with fine lines + wrinkles, collagen stimulation + wound healing + reducing the look of textural irregularities. So overall these ingredients help improve the overall look of the skin with continued use.

Other Peptides Included (Well-ageing): 9.0% Pure Undiluted Tripeptide-29: Helps the Copper Peptides work better and also improve collagen production.

4.0% Complex of Acetyl Tetrapeptide-2 and Trifluroacetyl Tripeptide-2: Also help with collagen stimulation and maintenance (helps with fine lines + elasticity).

Other skin-beneficial products: 0.10% Pure Mono-Dispersed Plant Glycogen: basically helps improve the dispersion of the peptides/actives onto the skin / Hyaluronic Acid Crosspolymer (Also in the Hada Labo Premium Lotion): lightweight and hydrating (not sticky and doesn’t just sit on top of the skin).

Full Ingredients: Aqua (Water), Glycerin, Tripeptide-29, Tripeptide-1 Copper Acetate, Tripeptide-1 Acetate, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin.

NOTE: The Incidecoder have a full ingredient breakdown HERE

Texture: A watery, liquid, light-blue serum. It’s very thin and will drip and flow down the face.

Sticky?: No.

Oily finish?: No.

Fast absorbing?: Yes.

Hydrating or Moisturising?: Slightly Hydrating.

As you can see this has a bright blue tint to it (does not tint the skin blue).


Does this Sting if the Skin has been Irritated / Sensitised by Shaving/Heavy Retinol Use?: Yes.

Summer or Winter?: Both Seasons (especially for oily skins).

Layerable?: Yes (no balling up).


Video Swatch:

As you can see this is an extremely lightweight watery serum. It definitely has some hydrating properties however.

Fragrance?: No added Fragrance and/or EO.

Good Under Makeup?: Yes.

How long have I been using this?: 3-4 Months.

Will I use until Completion?: Yes (should last another 2-3 months).

The Effect?: Slightly Hydrated skin that hopefully will aid in well-ageing and collagen stimulation! (For me this is more of a maintenance product and I think it helps with that!). However I do find this does encourage facial hair growth faster than normal.

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What I like:

  • Fragrance + EO Free
  • Vegan + Cruelty-Free
  • Very lightweight (Like a Solution)
  • Fast absorbing
  • Mildly Hydrating
  • Did not worsen the skin’s condition (helped maintain the skin’s condition)
  • Lasts a long time (I don’t need that much to cover the face and neck due to how lightweight this is)

What I don’t like:

  • I find quicker facial hair growth while using this
  • Will sting if the skin is irritated
  • Expensive

Overall Rating and Conclusion: 4 (nearly 3.9) /5 – This has helped maintain my skin’s condition (hasn’t made it look worse), HOWEVER I find that this really does encourage facial hair growth! This is expensive, so I’m glad a little goes a long way. It does sting if the skin is vulnerable so be weary. I enjoy the texture of this as it’s so lightweight. No I don’t enjoy the smell (copper), but I think it’s a great addition to add to a well-ageing routine but NOT replace your Retinoids (think of it as a good companion!).

Would I repurchase?: Yes.

Dupe?: The Dear Klais Midnight Blue Calming Serum LINK (However this doesn’t contain as much Copper as this serum).

My Skin Type: I am acne prone and have slightly dehydrated combo skin. My skin is usually tight where the cheeks and eye area is and the outer parts of my face. My T zone is oily. My skin isn’t a fan of thick/heavy formulas so I opt for lightweight formulas to prevent it from clogging up. My skin doesn’t like essential oils either and I try to avoid fragrance when I can.

Disclaimer: I am a skincare enthusiast and not a skin expert. I am not qualified to give out dermatological advice. This type of advice should only be given by a medical practitioner. Upon trying / using any of the reviewed products on the blog, please follow the manufacturer’s instructions and warnings and please seek medical advice if needed.

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